Pieris Pharmaceuticals Partner AstraZeneca Discontinue P-IIa Clinical Trial of Elarekibep (PRS-060/AZD1402) for the Treatment of Asthma
Shots:
- Pieris highlighted that its partner AstraZeneca has decided to stop dosing & discontinue the P-IIa trial evaluating elarekibep, an inhaled IL-4 receptor alpha inhibitor for the treatment of asthma
- The decision was based on a non-clinical 13wk. GLP toxicology study for the dry powder inhaler-formulated elarekibep which revealed inflammation-related lung tissue damage
- Pieris will expedite a review of the implications of the data. Additionally, the favorable longer-term non-clinical data would be essential to support later-stage advancement of the ongoing P-IIa study of elarekibep
Ref: Pieris Pharmaceuticals | Image: Pieris Pharmaceuticals
Related News:- Pieris Out-licenses PRS-342 to Boston Pharmaceuticals for ~$363M
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